Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982334 | 1.00 | KMT2A (0.54) | KMT2ACNR1CNR2ALOX5HPGD | |
| SCHEMBL16144713 | 0.90 | MAPT (0.48) | KMT2ACNR1CNR2ALOX5MAPT | |
| SCHEMBL16144705 | 0.90 | MAPT (0.48) | KMT2ACNR1CNR2ALOX5MAPT | |
| SCHEMBL14904735 | 0.90 | MAPT (0.48) | KMT2ACNR1CNR2ALOX5MAPT | |
| SCHEMBL14904771 | 0.89 | GAA (0.47) | KMT2ACNR1CNR2ALOX5MAPT | |
| SCHEMBL14280062 | 0.85 | KMT2A (0.47) | KMT2AHPGDMAPTHTTMGLL | |
| SCHEMBL11459789 | 0.84 | CNR1 (0.44) | CNR1CNR2ALOX5MAPTPDK2 | |
| SCHEMBL13980558 | 0.84 | KMT2A (0.46) | KMT2AHPGDHTTMEN1 | |
| SCHEMBL13468539 | 0.83 | CNR1 (0.53) | KMT2ACNR1CNR2ALOX5HTT | |
| SCHEMBL10724171 | 0.83 | CNR1 (0.53) | KMT2ACNR1CNR2ALOX5PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0987266-A1 | BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |