Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944 | 0.93 | TSHR (0.57) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| Ethylene Glycol SCHEMBL8134666 | 0.90 | TSHR (0.53) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| Methacrylic Acid SCHEMBL5826296 | 0.88 | TSHR (0.52) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL372427 | 0.87 | TSHR (0.50) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL23882527 | 0.85 | TSHR (0.49) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL16415673 | 0.85 | TSHR (0.49) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| Phosphoric Acid SCHEMBL2638501 | 0.85 | TSHR (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL8989287 | 0.84 | TSHR (0.55) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL14330403 | 0.84 | TSHR (0.46) | TSHRPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL3716634 | 0.84 | TSHR (0.47) | TSHRPRKCAPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289359-B2 | Self-adhesive multicomponent dental material | IVOCLAR VIVADENT AG (LI) | 2016-03-22 | — | — | US | disclosed |
| US-20100240795-A1 | SELF-ADHESIVE MULTICOMPONENT DENTAL MATERIAL | IVOCLAR VIVADENT AG (LI) | 2010-09-23 | — | — | US | disclosed |