Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MC4R | P32245 | 5/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eprazinone SCHEMBL20156 | 0.85 | ALDH1A1 (0.57) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| Eprazinone SCHEMBL21807703 | 0.84 | ALDH1A1 (0.60) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| Eprazinone SCHEMBL598430 | 0.84 | ALDH1A1 (0.60) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| Eprazinone SCHEMBL6429748 | 0.84 | ALDH1A1 (0.56) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| Eprazinone SCHEMBL1009370 | 0.77 | ALDH1A1 (0.39) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| Eprazinone SCHEMBL28086760 | 0.74 | ALDH1A1 (0.45) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| SCHEMBL12847710 | 0.67 | GAA (0.58) | ALDH1A1MC4RCHRM2DRD3CYP2D6 | |
| SCHEMBL14791780 | 0.67 | POLB (0.47) | LMNAALDH1A1SMN1; SMN2PAX8MITF | |
| SCHEMBL9170851 | 0.67 | ALDH1A1 (0.73) | LMNAALDH1A1MC4RMC1RSMN1; SMN2 | |
| SCHEMBL12847709 | 0.66 | POLB (0.55) | LMNAALDH1A1SMN1; SMN2PAX8JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |