Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.68 |
| ▸ | GABRP | O00591 | 3/20 | 0.68 |
| ▸ | GABRD | O14764 | 3/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.68 |
| ▸ | GABRE | P78334 | 3/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.68 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.68 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.68 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diazepam SCHEMBL8931438 | 0.93 | GABRA1 (0.79) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Diazepam SCHEMBL6823824 | 0.93 | GABRA1 (0.79) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Diazepam SCHEMBL1003950 | 0.91 | GABRA1 (0.70) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Flunitrazepam SCHEMBL8364961 | 0.89 | GABRA1 (0.64) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Flunitrazepam SCHEMBL28086646 | 0.86 | GABRA1 (0.75) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Fludiazepam SCHEMBL29440251 | 0.86 | GABRA1 (0.72) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Fludiazepam SCHEMBL29688065 | 0.86 | GABRA1 (0.72) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Fludiazepam SCHEMBL156039 | 0.86 | GABRA1 (0.72) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Fludiazepam SCHEMBL29564860 | 0.86 | GABRA1 (0.72) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Fludiazepam SCHEMBL29040947 | 0.84 | GABRA1 (0.70) | LMNAGABRA1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |