SCHEMBL2808652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2808655	1.00	ALDH1A1 (0.47)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL2812007	0.84	AKR1C3 (0.50)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL2812008	0.84	AKR1C3 (0.50)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL2808944	0.83	AKR1C3 (0.37)	ALDH1A1MAPTKMT2AMEN1SMN1; SMN2
	SCHEMBL2808943	0.83	AKR1C3 (0.37)	ALDH1A1MAPTKMT2AMEN1SMN1; SMN2
	SCHEMBL2812162	0.83	CYP2C9 (0.43)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL2812164	0.83	CYP2C9 (0.43)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL12851418	0.80	ALDH1A1 (0.42)	ALDH1A1LMNANPSR1MAPTKMT2A
	SCHEMBL2809764	0.78	TDP1 (0.55)	ALDH1A1MAPTKMT2AMEN1TDP1
	SCHEMBL2809761	0.78	TDP1 (0.55)	ALDH1A1MAPTKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.