SCHEMBL28086697

SCHEMBL28086697

C[C@@]12CCC[C@H]1[C@@H]1CCC3CCC(O)C[C@]3(C)[C@H]1CC2

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 1/20 0.68
CDK5 Q00535 1/20 0.56
CDK5R1 Q15078 1/20 0.56
GRIN1 Q05586 6/20 0.51
GRIN2B Q13224 6/20 0.51
AKR1B10 O60218 1/20 0.45
MBOAT4 Q96T53 1/20 0.43
LMNA P02545 2/20 0.42
GPBAR1 Q8TDU6 2/20 0.42
SHBG P04278 1/20 0.42
SERPINA6 P08185 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5842846 0.83 CDK5 (0.57) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL5842843 0.83 CDK5 (0.57) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL28142697 0.83 CDK5 (0.57) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL31315001 0.82 CDK5 (0.56) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL21206237 0.82 CDK5 (0.68) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL21206146 0.82 CDK5 (0.68) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL16385901 0.82 CDK5 (0.68) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL14883710 0.82 CDK5 (0.68) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL4442143 0.81 NR1I3 (0.59) NR1I3CDK5CDK5R1GRIN1GRIN2B
SCHEMBL20781172 0.81 NR1I3 (1.00) NR1I3CDK5CDK5R1GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115389648-A Method for detecting multiple steroid hormones in biological body fluid 上海体育学院 2022-11-25 CN disclosed
CN-108822175-A 3,16- androstenedione class compound and its application 昆明理工大学 2018-11-16 CN disclosed
CN-106749463-A A kind of method that methyltestosterone is reclaimed in the mother liquor from methyltestosterone 华中药业股份有限公司 2017-05-31 CN disclosed
CN-106589032-A Treatment method for methyltestosterone mother liquor 华中药业股份有限公司 2017-04-26 CN disclosed
CN-106163528-A Steroids for the treatment of hepatic encephalopathy 梅克芳识别有限公司 2016-11-23 CN disclosed