Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087184 | 1.00 | MAPT (0.47) | MAPTGAATSHRALDH1A1NOTUM | |
| SCHEMBL4135838 | 1.00 | MAPT (0.47) | MAPTGAATSHRALDH1A1NOTUM | |
| SCHEMBL16445419 | 0.86 | MAPT (0.45) | MAPTGAATSHR | |
| SCHEMBL23163268 | 0.86 | MAPT (0.45) | MAPTGAATSHRALDH1A1NOTUM | |
| SCHEMBL29155481 | 0.86 | MAPT (0.45) | MAPTGAATSHRALDH1A1NOTUM | |
| SCHEMBL29155482 | 0.86 | MAPT (0.45) | MAPTGAATSHRALDH1A1NOTUM | |
| SCHEMBL692724 | 0.84 | MAPT (0.44) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL599220 | 0.84 | MAPT (0.44) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL599219 | 0.84 | MAPT (0.44) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL599218 | 0.84 | MAPT (0.44) | MAPTGAATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764887-A | Nitrogen-containing saturated heterocyclic compound | 住友化学株式会社 | 2016-07-13 | — | — | CN | disclosed |