Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568534 | 0.86 | CYP2D6 (0.50) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL4176734 | 0.86 | OPRM1 (0.50) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL4183999 | 0.86 | OPRM1 (0.50) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL1716774 | 0.86 | OPRM1 (0.50) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL1281942 | 0.85 | CYP3A4 (0.56) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL14001236 | 0.82 | OPRM1 (0.53) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL29312728 | 0.81 | OPRM1 (0.53) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL14310852 | 0.79 | OPRM1 (0.49) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL14001234 | 0.78 | OPRM1 (0.49) | OPRM1OPRK1CYP2D6ALDH1A1MEN1 | |
| SCHEMBL11401193 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249732-B | The bacterial topoisomerase II of suppression 2-ethyl carbamyl amino-1,3-benzothiazole-5-base | 生物区欧洲有限公司 | 2016-08-10 | — | — | CN | disclosed |