Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938702 | 1.00 | TAAR1 (0.57) | TAAR1GAAKMT2AMEN1CA12 | |
| Hydrochloric Acid SCHEMBL28087267 | 0.98 | TAAR1 (0.55) | TAAR1GAAKMT2AMEN1CA12 | |
| Hydrochloric Acid SCHEMBL174859 | 0.98 | TAAR1 (0.55) | TAAR1GAAKMT2AMEN1CA12 | |
| Oxalic Acid SCHEMBL27962691 | 0.90 | GAA (0.52) | TAAR1GAAKMT2AMEN1CYP1A2 | |
| SCHEMBL13801229 | 0.89 | TAAR1 (0.53) | TAAR1GAAKMT2AMEN1CA12 | |
| SCHEMBL13644447 | 0.89 | TAAR1 (0.57) | TAAR1GAAKMT2AMEN1CA12 | |
| SCHEMBL12574171 | 0.85 | TAAR1 (0.53) | TAAR1GAAKMT2AMEN1CA12 | |
| SCHEMBL937041 | 0.85 | TAAR1 (0.53) | TAAR1GAAKMT2AMEN1CYP1A2 | |
| SCHEMBL23374696 | 0.84 | TAAR1 (0.52) | TAAR1GAAKMT2AMEN1CA12 | |
| Hydrochloric Acid SCHEMBL3770898 | 0.84 | TAAR1 (0.52) | TAAR1GAAKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924396-A | Method for preparing lorcaserin | 重庆两江药物研发中心有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-105924396-A | Method for preparing lorcaserin | 重庆两江药物研发中心有限公司 | 2016-09-07 | — | — | CN | disclosed |