Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16293188 | 0.91 | POLB (0.39) | ESR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16293255 | 0.82 | ESR1 (0.38) | ESR1SMN1; SMN2ELANE | |
| SCHEMBL14965047 | 0.79 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16293189 | 0.77 | HPGD (0.38) | ESR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14964997 | 0.74 | KDM4E (0.47) | SMN1; SMN2ALDH1A1CHRM3PDE4APDE4B | |
| SCHEMBL14969468 | 0.70 | STAT3 (0.44) | — | |
| SCHEMBL16293285 | 0.70 | MEN1 (0.48) | SMN1; SMN2 | |
| SCHEMBL11202279 | 0.69 | ESR1 (0.49) | ESR1SMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL27978754 | 0.68 | STAT3 (0.43) | — | |
| SCHEMBL14965510 | 0.66 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011054-B | As the thieno of potassium channel inhibitors and Furanopyrimidines class and pyridines | 森申有限公司 | 2016-08-24 | — | — | CN | disclosed |