SCHEMBL28087680

SCHEMBL28087680

C=CC(=O)OCCC[SiH2]OCC.CO[SiH3]

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 4/20 0.49
CYP3A4 P08684 2/20 0.49
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 2/20 0.39
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28174477 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1015223 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
Phosphine SCHEMBL28175773 0.92 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
Propene SCHEMBL28137991 0.91 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
Hydrochloric Acid SCHEMBL28159246 0.91 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28110497 0.90 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
Trimethylammonium SCHEMBL28223811 0.89 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28029882 0.89 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28119923 0.89 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27999143 0.89 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106164167-B Polyacetal resin composite and its formed body 旭化成株式会社 2018-10-02 CN disclosed
CN-108026352-A Polyacetal resin composition and molded article thereof 旭化成株式会社 2018-05-11 CN disclosed
CN-108028376-A Anode for nonaqueous electrolyte secondary battery active material and anode 松下知识产权经营株式会社 2018-05-11 CN disclosed
CN-105358624-B Resin combination, prepreg and laminate 松下知识产权经营株式会社 2017-06-06 CN disclosed
CN-106554596-A Resin-made guiding parts, resin-made guiding parts polyacetal resin composite and their manufacture method 旭化成株式会社 2017-04-05 CN disclosed
CN-106554597-A The manufacture method of resin gears, resin gears polyacetal resin composite, its manufacture method and resin gears 旭化成株式会社 2017-04-05 CN disclosed
CN-106164167-A Polyacetal resin composite and molded body thereof 旭化成株式会社 2016-11-23 CN disclosed
CN-105934307-A Roughened copper foil, copper-clad laminate, and printed wiring board 三井金属矿业株式会社 2016-09-07 CN disclosed