Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 6/20 | 0.69 |
| ▸ | CDK1 | P06493 | 6/20 | 0.69 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.69 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.69 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.58 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | DNM2 | P50570 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830086 | 0.99 | CCNB2 (0.67) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL11829824 | 0.99 | CCNB2 (0.67) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL11834537 | 0.99 | CCNB2 (0.67) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL11841743 | 0.95 | CCNB2 (0.63) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL11831182 | 0.82 | YTHDC1 (0.61) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL3234796 | 0.82 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL11831368 | 0.79 | YTHDC1 (0.58) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL2808798 | 0.78 | CCNB2 (0.56) | CCNB2CDK1CCNB1CCNB3LMNA | |
| SCHEMBL11829828 | 0.77 | CCNB2 (0.55) | CCNB2CDK1CCNB1CCNB3LMNA | |
| SCHEMBL11830093 | 0.77 | CCNB2 (0.55) | CCNB2CDK1CCNB1CCNB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203451-B1 | SUBSTITUTED 6-(ALKYLBENZYLAMINO)PURINE DERIVATIVES FOR USE AS CYTOKININ RECEPTOR ANTAGONISTS AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2014-07-30 | — | — | EP | disclosed |
| US-20130130906-A1 | SUBSTITUTED 6-(ALKYLBENZYLAMINO) PURINE DERIVATIVES FOR USE AS CYTOKININ RECEPTOR ANTAGONISTS AND PREPARATIONS CONTAINING THESE DERIVATIVES | FREIE UNIVERSITAT BERLIN (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240537-A1 | Substituted 6-(alkylbenzylamino)purine derivatives for use as cytokinin receptor antagonists and preparations containing these derivatives | FREIE UNIVERSITAT BERLIN (DE) | 2010-09-23 | — | — | US | disclosed |
| US-4282361-A | Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-08-04 | — | — | US | disclosed |
| US-3988338-A | PLANT GROWTH REGULATORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130130906-A1 | SUBSTITUTED 6-(ALKYLBENZYLAMINO) PURINE DERIVATIVES FOR USE AS CYTOKININ RECEPTOR ANTAGONISTS AND PREPARATIONS CONTAINING THESE DERIVATIVES | ADORA2A, ADORA1, GART | CCNB2 511/4885CDK1 402/4885CCNB1 317/4885 |
| US-20100240537-A1 | Substituted 6-(alkylbenzylamino)purine derivatives for use as cytokinin receptor antagonists and preparations containing these derivatives | ADORA2A, P2RY6, P2RY1 | CCNB2 599/4885CDK1 444/4885CCNB1 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.