Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088246 | 1.00 | NOD1 (0.51) | NOD1GRIK1GRIK2TSHRNAAA | |
| SCHEMBL5168757 | 0.94 | NOD1 (0.44) | NOD1GRIK1GRIK2TSHRP2RY10 | |
| SCHEMBL6574312 | 0.94 | NOD1 (0.44) | NOD1GRIK1GRIK2TSHRP2RY10 | |
| SCHEMBL6574319 | 0.94 | NOD1 (0.44) | NOD1GRIK1GRIK2TSHRP2RY10 | |
| SCHEMBL109807 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 | |
| SCHEMBL109803 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 | |
| SCHEMBL109804 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 | |
| SCHEMBL111055 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 | |
| SCHEMBL112301 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 | |
| SCHEMBL109805 | 0.94 | TSHR (0.49) | NOD1TSHRNAAAHCAR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820138-A | ABT-263 crystalline forms and solvates for use in treating BCL-2 protein related diseases | ABBVIE 公司 | 2016-08-03 | — | — | CN | disclosed |