Trioxsalen

Trioxsalen

SCHEMBL28088632

Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1.N#Cc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
KDM4E B2RXH2 4/20 0.71
CYP1A2 P05177 3/20 0.71
MAOA P21397 2/20 0.71
CYP3A4 P08684 1/20 0.71
HTR2C P28335 1/20 0.71
MAPK1 P28482 1/20 0.71
ADORA2A P29274 1/20 0.71
KCNA3 P22001 8/20 0.46
KMT2A Q03164 1/20 0.43
MAOB P27338 2/20 0.41
CYP1A1 P04798 2/20 0.40
CYP1B1 Q16678 2/20 0.40
ATM Q13315 1/20 0.40
HPGD P15428 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 1/20 0.39
XDH P47989 1/20 0.38
SLC22A12 Q96S37 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trioxsalen SCHEMBL28285134 0.86 KDM4E (0.85) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL4954831 0.84 KDM4E (1.00) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL1252 0.84 KDM4E (1.00) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL29432841 0.84 KDM4E (1.00) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL11442670 0.83 KDM4E (0.97) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL28103198 0.78 KDM4E (0.85) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL28215231 0.78 KDM4E (0.85) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL28089383 0.78 KDM4E (0.85) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL28143570 0.76 KDM4E (0.81) ALDH1A1KDM4ECYP1A2MAOACYP3A4
Trioxsalen SCHEMBL28205170 0.76 KDM4E (0.81) ALDH1A1KDM4ECYP1A2MAOACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793269-B Benzobis (thiadiazole) derivative, the ink containing it and the organic electronic device containing it 宇部兴产株式会社 2018-01-09 CN disclosed
CN-105793269-A Benzobis(thiadiazole) derivative, ink containing same, and organic electronic device using same 宇部兴产株式会社 2016-07-20 CN disclosed