Pyrimidine

Pyrimidine

SCHEMBL28088660

Brc1cccs1.c1cncnc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.41
CYP2E1 P05181 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2B6 P20813 1/20 0.41
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
NAPRT Q6XQN6 1/20 0.35
CYP17A1 P05093 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
LMNA P02545 1/20 0.32
PTBP1 P26599 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28219020 0.91 TSHR (0.45) CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6
SCHEMBL4767521 0.83
SCHEMBL22395 0.83
SCHEMBL1254977 0.83 FBP1 (0.41) TSHRTDP1KDM4EALDH1A1HPGD
Cyanide SCHEMBL27917171 0.80
Benzene SCHEMBL28756946 0.80 DAO (0.40) TSHRTDP1KDM4EALDH1A1HPGD
Hydrogen Sulfide SCHEMBL29248840 0.80
SCHEMBL3805323 0.80
Water SCHEMBL625172 0.80 FBP1 (0.39) TSHRTDP1KDM4EALDH1A1HPGD
Iodide SCHEMBL1306389 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105765031-A Novel light-emitting compound and organic light-emitting element comprising same 东进世美肯株式会社 2016-07-13 CN disclosed