SCHEMBL28088686

SCHEMBL28088686

C=C(C)C(=O)C(O)CO[PH](=O)OCC[N+](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 6/20 0.36
CHRM1 P11229 6/20 0.36
CHRM3 P20309 6/20 0.36
CHRM2 P08172 5/20 0.36
CHRM4 P08173 5/20 0.36
CHRNB2 P17787 4/20 0.36
CHRNA4 P43681 4/20 0.36
CHRNA7 P36544 3/20 0.36
HTR1A P08908 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PGR P06401 1/20 0.36
TBXA2R P21731 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA10 Q9GZZ6 1/20 0.36
CHRNA9 Q9UGM1 1/20 0.36
GALR3 O60755 2/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.35
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28088691 0.87 CHRM2 (0.31) CHRM1CHRM3CHRM2
SCHEMBL28303581 0.86 TSHR (0.30) TSHR
SCHEMBL28248034 0.83 TSHR (0.35) MAPTTSHR
SCHEMBL28701633 0.81 CHRM5 (0.37) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL28355454 0.75 CHRM1 (0.40) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL28643330 0.75 CHRM5 (0.40) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL28022249 0.74 TSHR (0.34) TSHR
SCHEMBL6278177 0.74 THRB (0.46) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL159440 0.73 SMN1; SMN2 (0.50) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL2022215 0.73 CHRM5 (0.41) CHRM5CHRM1CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110051886-A The medical device and method that antithrombotic generates 柯惠有限合伙公司 2019-07-26 CN claimed
CN-105744965-B Antithrombotic medical devices and methods 柯惠有限合伙公司 2019-07-09 CN claimed
CN-104203366-B Mildew-resistant air filter filtering material and mildew-resistant air filter 日油株式会社 2016-08-24 CN claimed
CN-110051886-A The medical device and method that antithrombotic generates 柯惠有限合伙公司 2019-07-26 CN disclosed
CN-105744965-B Antithrombotic medical devices and methods 柯惠有限合伙公司 2019-07-09 CN disclosed
CN-104203366-B Mildew-resistant air filter filtering material and mildew-resistant air filter 日油株式会社 2016-08-24 CN disclosed