Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879221 | 0.80 | MAPT (0.39) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL657923 | 0.79 | MAPT (0.46) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL563397 | 0.78 | F10 (0.43) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL20475388 | 0.76 | KDM4E (0.44) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL1269548 | 0.75 | F10 (0.44) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL1269176 | 0.74 | MAPT (0.46) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL20475361 | 0.74 | MAPT (0.46) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL482069 | 0.74 | MAPT (0.46) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL9294262 | 0.74 | F2 (0.50) | MAPTLMNAKDM4EF10F2 | |
| SCHEMBL20475336 | 0.73 | KDM4E (0.41) | MAPTLMNAKDM4EF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849101-A | Novel imidazolidine-2,4-dione derivatives | 益普生制药股份有限公司 | 2016-08-10 | — | — | CN | disclosed |