Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269548 | 0.87 | F10 (0.44) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL20475361 | 0.86 | MAPT (0.46) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL1269176 | 0.86 | MAPT (0.46) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL482069 | 0.86 | MAPT (0.46) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL657923 | 0.86 | MAPT (0.46) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL698333 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CPA1NPC1 | |
| SCHEMBL29921355 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CPA1NPC1 | |
| SCHEMBL31115525 | 0.85 | F2 (0.47) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL1269160 | 0.85 | ALOX15 (0.46) | F2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL232194 | 0.85 | F2 (0.59) | F2ALDH1A1TSHRF10MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530130-A | Preparation method of henibut | 杭州国瑞生物科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-110407730-B | Pyrrolidone herbicides | FMC 公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-111393312-A | Preparation method for synthesizing 4-amino-3-phenylbutyric acid hydrochloride by one-pot method and product prepared by same | 福建科宏生物工程股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| EP-0436334-B1 | 3-Aminopiperidine derivatives and related nitrogen containing heterocycles | PFIZER (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5332817-A | 3-aminopiperidine derivatives and related nitrogen containing heterocycles | PFIZER INC. (US) | 1994-07-26 | — | — | US | disclosed |
| US-5232929-A | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| WO-1991009844-A1 | SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |
| EP-0436334-A2 | 3-Aminopiperidine derivatives and related nitrogen containing heterocycles | PFIZER INC. (US) | 1991-07-10 | — | — | EP | disclosed |