Pyridine

Pyridine

SCHEMBL28088917

CC1(C)CNCC(C)(C)N1.c1ccncc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28237640 0.87 TSHR (0.32) TSHRNAPRTTDP1KDM4EALDH1A1
Pyridine SCHEMBL28139381 0.81 TSHR (0.43) TSHRNAPRTTDP1
Pyridine SCHEMBL28178726 0.79 TSHR (0.36) TSHRNAPRTTDP1KDM4EALDH1A1
Pyridine SCHEMBL28106888 0.77 TSHR (0.39) TSHRNAPRTTDP1
SCHEMBL4071694 0.76 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2
Pyridine SCHEMBL28210200 0.74 TSHR (0.36) TSHRNAPRTTDP1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL34473678 0.73 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL677357 0.73 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2
Pyridine SCHEMBL11825162 0.70
Pyridine SCHEMBL27870675 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234654-A The synthetic method of 2,2,6,6- tetramethyl piperidine sodium classes 株式会社神钢环境舒立净 2019-09-13 CN claimed
CN-104837853-B Bisphosphite mixture and use thereof as catalyst mixture in hydroformylation 赢创德固赛有限公司 2017-05-10 CN claimed
CN-104854118-B Various different asymmetric diphosphite ester admixtures and as catalyst mixture purposes in hydroformylation 赢创德固赛有限公司 2016-12-14 CN claimed
CN-104837852-B The mixture of the bis-phosphite of structural isomerism 赢创德固赛有限公司 2016-11-09 CN claimed
CN-110358360-A Pigment printing and dyeing inkjet ink composition and pigment printing and dyeing ink jet recording method 精工爱普生株式会社 2019-10-22 CN disclosed
CN-110248969-A Method for continuous synthesis of modified diene elastomers using lithium amide initiators 米其林集团总公司 2019-09-17 CN disclosed
CN-110128878-A Pigment printing and dyeing inkjet ink composition, pigment printing and dyeing inkjet ink composition group and inkjet pigments dyeing method 精工爱普生株式会社 2019-08-16 CN disclosed
CN-110099892-A Method for using N-oxyl polymerization inhibitors in a wash settler for the production of methyl methacrylate 陶氏环球技术有限责任公司 2019-08-06 CN disclosed
CN-106459345-B Fast drying, elastic energy, scratch resistant and stable coating compounds 巴斯夫欧洲公司 2019-02-22 CN disclosed
CN-109153662-A Preparation method of glycerol carbonate 英国贝尔法斯特女王大学 2019-01-04 CN disclosed
CN-105324379-B Benzimidazole derivatives as bromodomain inhibitors 吉利德科学公司 2018-12-04 CN disclosed
CN-105829485-B Photocurable composition with adhesiveness 思美定株式会社 2018-10-12 CN disclosed
CN-108341777-A Compound of isobioquin group and its application 四川科伦博泰生物医药股份有限公司 2018-07-31 CN disclosed
CN-108329375-A Preparation method of steroid compound 南方科技大学 2018-07-27 CN disclosed
CN-106459345-A Fast drying, elastic energy, scratch resistant and stable coating compounds 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-103864754-B Five-membered azole heterocycle compound and preparation method thereof, pharmaceutical composition and purposes 中国科学院上海药物研究所 2016-12-21 CN disclosed
CN-106008941-A Imidazolyl dyeable modified copolyester for anionic dye and preparation and application of imidazolyl dyeable modified copolyester 东华大学 2016-10-12 CN disclosed
CN-106008942-A Imidazole-based anionic dye dyeable modified copolyester masterbatch, and preparation and application thereof 东华大学 2016-10-12 CN disclosed
CN-103459405-B Process for producing transition metal complex, catalyst for trimerization, process for producing 1-hexene, process for producing substituted cyclopentadiene compound (1) 住友化学株式会社 2016-09-28 CN disclosed
CN-105960416-A Producing propylene impact copolymers and products 格雷斯公司 2016-09-21 CN disclosed