SCHEMBL677357

SCHEMBL677357

CC1(C)CNCC(C)(C)N1.[LiH]

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071694 0.96 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL34473678 0.92 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1
Piperazine SCHEMBL28858011 0.86 HIF1A (0.40) SMN1; SMN2ALDH1A1
SCHEMBL1617509 0.74 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL1928918 0.72 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1
SCHEMBL2010663 0.70
SCHEMBL29414201 0.70
SCHEMBL243842 0.70
SCHEMBL13326775 0.70
SCHEMBL9522660 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470702-B1 An optically active morpholino oxobutyric acid hydroxy binaphthalene derivative and its preparation TAKASAGO PERFUMERY CO LTD (JP) 1995-09-27 EP claimed
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA (JP) 2017-07-06 US disclosed
US-9655362-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-05-23 US disclosed
CN-104487419-B Pyridine derivate and the method being used for producing the midbody compound of sulfonylurea herbicide with its preparation 株式会社LG生命科学 2016-08-24 CN disclosed
CN-104487419-A Novel pyridine derivatives and method for preparation of intermediate compound for producing sulfonylurea herbicides using the same LG LIFE SCIENCES LTD 2015-04-01 CN disclosed
US-8653277-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
US-8653113-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
WO-2014010990-A1 NOVEL PYRIDINE DERIVATIVES AND METHOD FOR PREPARATION OF INTERMEDIATE COMPOUND FOR PRODUCING SULFONYLUREA HERBICIDES USING THE SAME LG LIFE SCIENCES LTD. (KR) 2014-01-16 WO disclosed
US-8609150-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-12-17 US disclosed
EP-2351762-B1 NOVEL PYRIMIDINE DERIVATIVE AND METHOD FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR INTERMEDIATE KANEKA CORP (JP) 2013-10-16 EP disclosed
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-01 US disclosed
US-20090209768-A1 NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID KANEKA CORPORATION (JP) 2009-08-20 US disclosed
CN-101495494-A Fused ring spiroketal derivative and use thereof as therapeutic agent for diabetes CHUGAI PHARMACEUTICAL CO LTD (JP) 2009-07-29 CN disclosed
EP-2050738-A1 NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2009-04-22 EP disclosed
EP-2048152-A1 FUSED RING SPIROKETAL DERIVATIVE AND USE THEREOF AS DRUG FOR TREATING DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2009-04-15 EP disclosed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US disclosed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP disclosed
EP-0470702-B1 An optically active morpholino oxobutyric acid hydroxy binaphthalene derivative and its preparation TAKASAGO PERFUMERY CO LTD (JP) 1995-09-27 EP disclosed
US-5106970-A OPTICALLY ACTIVE 4-MORPHOLINO-2-(1-NAPHTHYLMETHYL)-4-OXOBUTYRIC ACID 2'-HYDROXY-1,1'BINAPHTHALEN-2-YL TAKASAGO INTERNATIONAL CORPORATION (JP) 1992-04-21 US disclosed
EP-0470702-A1 An optically active morpholino oxobutyric acid hydroxy binaphthalene derivative and its preparation Takasago International Corporation (JP) 1992-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CBR1, CNPY2 SMN1; SMN2 1901/4885ALDH1A1 1897/4885
US-20090209768-A1 NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID DAO, RCC2, AADAT SMN1; SMN2 4627/4885ALDH1A1 2987/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH SMN1; SMN2 2015/4885ALDH1A1 1250/4885
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH SMN1; SMN2 2015/4885ALDH1A1 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.