Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095969 | 0.80 | ACACB (0.50) | ACACBMAPK1CYP3A4PKMALOX15 | |
| SCHEMBL23554569 | 0.77 | ACACB (0.40) | ACACBCACNA1HCACNA1GCACNA1ICHEK1 | |
| SCHEMBL9935890 | 0.77 | ACACB (0.50) | ACACBCACNA1HFFAR1CACNA1GCACNA1I | |
| SCHEMBL14152713 | 0.75 | CNR2 (0.61) | ACACBCACNA1HCNR2CACNA1GCACNA1I | |
| SCHEMBL17316355 | 0.74 | ACACB (0.54) | ACACBCACNA1HFFAR1KDM4ECACNA1G | |
| SCHEMBL1403507 | 0.74 | P4HTM (0.63) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL15262867 | 0.74 | PLA2G2A (0.43) | ACACBCACNA1HFFAR1CACNA1GCACNA1I | |
| SCHEMBL30703582 | 0.73 | HPGD (0.43) | P4HTMACACBALDH1A1MEN1CYP1A2 | |
| SCHEMBL29423325 | 0.73 | CNR2 (0.57) | CNR2 | |
| SCHEMBL15776479 | 0.73 | CNR2 (0.57) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-106349156-B | It can be used as the pyridine -2- amides of CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |