Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791762 | 0.77 | KMT2A (0.46) | MCL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28088871 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21812440 | 0.72 | MCL1 (0.58) | MCL1ALDH1A1MEN1KMT2AHTR7 | |
| SCHEMBL12278059 | 0.72 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL12278882 | 0.72 | MEN1 (0.39) | ALDH1A1MEN1KMT2AGSK3B | |
| SCHEMBL12279285 | 0.72 | ALDH1A1 (0.44) | MCL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25599594 | 0.71 | ALDH1A1 (0.47) | ALDH1A1NPC1MAPTRAB9AHTT | |
| SCHEMBL2382747 | 0.71 | MCL1 (0.56) | MCL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL17422809 | 0.69 | MCL1 (0.54) | MCL1ALDH1A1MEN1KMT2AHTR7 | |
| SCHEMBL17678213 | 0.69 | NPC1 (0.48) | ALDH1A1MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859639-A | NOVEL ANTI-INFLAMMATORY AGENTS | 雷斯韦洛吉克斯公司 | 2016-08-17 | — | — | CN | disclosed |