Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.86 |
| ▸ | CDK5 | Q00535 | 16/20 | 0.86 |
| ▸ | CDK5R1 | Q15078 | 16/20 | 0.86 |
| ▸ | GSK3A | P49840 | 15/20 | 0.86 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.86 |
| ▸ | CDK1 | P06493 | 7/20 | 0.86 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.86 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.86 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.86 |
| ▸ | CDK2 | P24941 | 3/20 | 0.86 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.86 |
| ▸ | ABL1 | P00519 | 2/20 | 0.86 |
| ▸ | LCK | P06239 | 2/20 | 0.86 |
| ▸ | FYN | P06241 | 2/20 | 0.86 |
| ▸ | PIM1 | P11309 | 2/20 | 0.86 |
| ▸ | FLT4 | P35916 | 2/20 | 0.86 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.86 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azakenpaullone SCHEMBL29363781 | 0.93 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| Azakenpaullone SCHEMBL378920 | 0.93 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379389 | 0.80 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378921 | 0.80 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL22570392 | 0.80 | GSK3B (0.76) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378333 | 0.80 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379540 | 0.80 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378917 | 0.80 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL24393915 | 0.79 | GSK3B (0.74) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379385 | 0.79 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106086071-B | A kind of iPSCs of non-viral iPSCs abductive approach and its inducing composition, kit and its acquisition | 广州市搏克生物技术有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-106086071-A | A kind of non-viral iPSCs abductive approach and the iPSCs of inducing composition, test kit and acquisition thereof thereof | 广州市搏克生物技术有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105861447-A | Non-virus iPSCs induction composition and kit thereof | 广州市搏克生物技术有限公司 | 2016-08-17 | — | — | CN | disclosed |