Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 16/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 16/20 | 1.00 |
| ▸ | GSK3A | P49840 | 15/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 7/20 | 1.00 |
| ▸ | CDK1 | P06493 | 7/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 7/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 3/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 3/20 | 1.00 |
| ▸ | ABL1 | P00519 | 2/20 | 1.00 |
| ▸ | LCK | P06239 | 2/20 | 1.00 |
| ▸ | FYN | P06241 | 2/20 | 1.00 |
| ▸ | PIM1 | P11309 | 2/20 | 1.00 |
| ▸ | FLT4 | P35916 | 2/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azakenpaullone SCHEMBL29363781 | 1.00 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| Azakenpaullone SCHEMBL28089101 | 0.93 | GSK3B (0.86) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378921 | 0.86 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379389 | 0.86 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL22570392 | 0.86 | GSK3B (0.76) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378333 | 0.86 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379540 | 0.86 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL378917 | 0.86 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL379385 | 0.85 | GSK3B (1.00) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL24393915 | 0.83 | GSK3B (0.74) | GSK3BCDK5CDK5R1GSK3ACCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070916-A | Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-22 | — | — | CN | claimed |
| CN-122038274-A | Method for inducing differentiation and maturation of alveolar organoids and application thereof | 广州国家实验室 | 2026-05-15 | — | — | CN | claimed |
| CN-122038284-A | Method for inducing differentiation of anterior foregut endoderm cells to form lung progenitor cells and application thereof | 广州国家实验室 | 2026-05-15 | — | — | CN | claimed |
| US-20260132380-A1 | Hepatocyte Expansion Methods | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2026-05-14 | — | — | US | claimed |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| US-12618045-B2 | Automated method for preparing retinal pigment epithelium cells | CENTRE D'ETUDE DES CELLULES SOUCHES (CECS) (FR) | 2026-05-05 | — | — | US | claimed |
| US-20260108514-A1 | METHOD OF INHIBITING EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER METASTASIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-04-23 | — | — | US | claimed |
| US-20260015632-A1 | CULTURE MEDIUM COMBINATION FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CD34+ HEMATOPOIETIC STEM/PROGENITOR CELLS | SHENZHEN CELL INSPIRE BIOTECHNOLOGY CO., LTD. (CN) | 2026-01-15 | — | — | US | claimed |
| US-12497593-B2 | Generation of hematopoietic progenitor cells from human pluripotent stem cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-12-16 | — | — | US | claimed |
| US-12497596-B2 | Hepatocyte expansion methods | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2025-12-16 | — | — | US | claimed |
| WO-2018160028-A1 | MEDIUM COMPOSITION FOR NEURON DIFFERENTIATION AND METHOD FOR DIFFERENTIATING SOMATIC CELLS INTO NEURONS USING SAME MEDIUM COMPOSITION | 주식회사 셀라토즈테라퓨틱스 | 2018-09-07 | — | — | WO | claimed |
| WO-2018155913-A1 | METHOD FOR DIFFERENTIATION INTO SKELETAL MUSCLE CELL USING LOW-MOLECULAR WEIGHT COMPOUND | 성균관대학교산학협력단 | 2018-08-30 | — | — | WO | claimed |
| EP-3350313-A1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | Agency For Science, Technology And Research (A*star) (SG) | 2018-07-25 | — | — | EP | claimed |
| WO-2017048193-A1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) | 2017-03-23 | — | — | WO | claimed |
| EP-3060649-A1 | REPROGRAMMING CARDIOMYOCYTES WITH ONE TRANSCRIPTION FACTOR | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-08-31 | — | — | EP | claimed |
| US-20160186141-A1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE CARDIOMYOCYTES | The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Glad | 2016-06-30 | — | — | US | claimed |
| US-20150307839-A1 | MATURATION OF HEPATOCYTE-LIKE CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS | TAKARA BIO EUROPE AB (SE) | 2015-10-29 | — | — | US | claimed |
| WO-2015061568-A1 | REPROGRAMMING CARDIOMYOCYTES WITH ONE TRANSCRIPTION FACTOR | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2015-04-30 | — | — | WO | claimed |
| US-8883502-B2 | Expandable cell source of neuronal stem cell populations and methods for obtaining and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-11 | — | — | US | claimed |
| US-20130236436-A1 | EXPANDABLE CELL SOURCE OF NEURONAL STEM CELL POPULATIONS AND METHODS FOR OBTAINING AND USNIG THEM | ZHANG KANG (US) | 2013-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108514-A1 | METHOD OF INHIBITING EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER METASTASIS | HDAC5, HDAC6, GSK3B | GSK3B 3/4885CDK5 283/4885CDK5R1 532/4885 |
| US-12618045-B2 | Automated method for preparing retinal pigment epithelium cells | WNT3A, BRSK1, BMP2K | GSK3B 16/4885CDK5 1136/4885CDK5R1 1454/4885 |
| US-20260015632-A1 | CULTURE MEDIUM COMBINATION FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CD34+ HEMATOPOIETIC STEM/PROGENITOR CELLS | KIT, JAK1, HGF | GSK3B 94/4885CDK5 2044/4885CDK5R1 1115/4885 |
| US-20160186141-A1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE CARDIOMYOCYTES | MYLK2, TNNI3, TNNT2 | GSK3B 795/4885CDK5 2467/4885CDK5R1 2166/4885 |
| US-20260132380-A1 | Hepatocyte Expansion Methods | HGF, CTNND1, MET | GSK3B 8/4885CDK5 479/4885CDK5R1 1579/4885 |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | WNT3A, GSK3B, GSK3A | GSK3B 2/4885CDK5 919/4885CDK5R1 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.