Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701819 | 0.90 | TSHR (0.40) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL8360690 | 0.87 | TSHR (0.38) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL3640654 | 0.87 | CHRM2 (0.42) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Bicarbonate SCHEMBL378701 | 0.86 | FFAR3 (0.44) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Bicarbonate SCHEMBL60768 | 0.86 | FFAR3 (0.44) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Hypochlorous Acid SCHEMBL1019174 | 0.86 | — | — | |
| SCHEMBL3640104 | 0.84 | TSHR (0.43) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Bicarbonate SCHEMBL4312446 | 0.83 | FFAR3 (0.41) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL216302 | 0.83 | FFAR3 (0.41) | FFAR3TSHRCHRM2CHRM4CHRM5 | |
| Acetic Acid SCHEMBL16244302 | 0.83 | FFAR3 (0.50) | FFAR3TSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107073136-A | Pyrrolobenzodiazepines Zhuo and its antibody disulphide conjugate | 健泰科生物技术公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-105848685-A | Peptidomimetic compounds and antibody-drug conjugates thereof | 健泰科生物技术公司 | 2016-08-10 | — | — | CN | disclosed |