Bicarbonate

Bicarbonate

SCHEMBL60768

CCN(CC)CC.O=C(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.44
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
CA9 Q16790 3/20 0.39
CA2 P00918 2/20 0.39
CA1 P00915 2/20 0.39
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
AGTR1 P30556 1/20 0.37
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 3/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL378701 1.00 FFAR3 (0.44) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL4800886 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL28088226 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL28103153 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL4800891 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL4312446 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL28065786 0.96 FFAR3 (0.41) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL10783748 0.93 ALDH1A1 (0.40) FFAR3CHRM2CHRM4CHRM5CHRM1
Bicarbonate SCHEMBL28333973 0.93 FFAR3 (0.39) FFAR3CHRM2CHRM4CHRM5CHRM1
Isobutane SCHEMBL27500548 0.90 CHRM2 (0.43) FFAR3CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7415 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091106-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING STABILIZED ENVELOPED VIRUSES BY SPRAY-DRYING AND LYOPHILIZATION UNIV COLORADO REGENTS (US) 2026-04-02 US claimed
US-20260060936-A1 INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS TECHNION RES & DEV FOUNDATION (IL) 2026-03-05 US claimed
CN-121577809-A Preparation of phosphorylated peptide fragment and space phosphorylated proteomics detection method 北京市神经外科研究所 2026-02-27 CN claimed
US-12552827-B2 Synthesis of an antiviral azasugar triphosphate BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-17 US claimed
US-20260014093-A1 ATOMIC LAYER DEPOSITION (ALD) PROCESSES APPLIED TO PHAGE AND PHAGE-LIKE PARTICLE PLATFORM YIELD THERMOSTABLE THERAPEUTIC AGENTS UNIV COLORADO REGENTS (US) 2026-01-15 US claimed
US-20260014251-A1 COMPOSITIONS, METHODS, AND USES FOR POLYNUCLEOTIDE FORMULATIONS FOR DRYING AND PROLONGED STORAGE VITRIVAX INC (US) 2026-01-15 US claimed
EP-4658076-A1 ANTISEPTIC CONDITIONING FORMULATIONS Thommen Medical AG (CH) 2025-12-10 EP claimed
EP-4651855-A1 COMPOSITIONS, METHODS, AND USES FOR POLYNUCLEOTIDE FORMULATIONS FOR DRYING AND PROLONGED STORAGE Vitrivax, Inc. (US) 2025-11-26 EP claimed
US-20250352633-A1 COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE BROAD-SPECTRUM HUMAN PAPILLOMAVIRUS FORMULATIONS UNIV COLORADO REGENTS (US) 2025-11-20 US claimed
US-20250334596-A1 ISOTOPIC LABELS FOR QUANTITATIVE MASS SPECTROMETRY OF LIPID ISOMERS TEXAS A & M UNIV SYS (US) 2025-10-30 US claimed
EP-0704536-A1 Method for the isolation and purification of nucleotid-activated sugars from biological sources HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP claimed
US-5208160-A METHODS AND APPARATUS FOR THE CONTINUOUS TREATMENT OF BIOLOGICAL SAMPLES SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-04 US claimed
EP-0502298-A2 Process for the stereo-selective preparation of beta-fucopyranosyl phosphates and very pure GDP-fucose MERCK PATENT GmbH (DE) 1992-09-09 EP claimed
US-4997927-A Adsorption GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) (DE) 1991-03-05 US claimed
EP-0174525-B1 PROCESS FOR THE PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1990-08-08 EP claimed
US-4844744-A Liquid, phosphate-free single phase degreasing compositions HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-07-04 US claimed
EP-0174525-A2 Process for the purification of synthetic oligonucleotides Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1986-03-19 EP claimed
US-4448883-A CONTROLLING PH, IONIC AND PROTEIN CONCENTRATION THE MIDLAND CERTIFIED REAGENT COMPANY (US) 1984-05-15 US claimed
EP-0102661-A1 A paper for RNA blotting; a process for making same; applications of the paper Katholieke Universiteit, Faculteit der Wiskunde en Natuurwetenschappen (NL) 1984-03-14 EP claimed
US-4417079-A FROM BUTADIENE AND WATER, PHOSPHINE-PALLADIUM CATALYST KURARAY COMPANY, LIMITED (JP) 1983-11-22 US claimed