Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.72 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458748 | 0.93 | TAAR1 (0.75) | TAAR1MAOAIDO1GPR52 | |
| SCHEMBL29423333 | 0.84 | TAAR1 (1.00) | TAAR1IDO1HRH1MPOGPR52 | |
| SCHEMBL265615 | 0.84 | TAAR1 (1.00) | TAAR1IDO1HRH1MPOGPR52 | |
| SCHEMBL3680377 | 0.84 | MAOA (0.61) | TAAR1MAOAHRH1MPOSLC6A4 | |
| SCHEMBL5040860 | 0.83 | TAAR1 (0.59) | TAAR1IDO1GPR52 | |
| SCHEMBL9175222 | 0.83 | TAAR1 (0.59) | TAAR1IDO1GPR52 | |
| Bromide SCHEMBL31622102 | 0.82 | TAAR1 (0.95) | TAAR1IDO1HRH1MPOGPR52 | |
| Iodide SCHEMBL28685278 | 0.82 | TAAR1 (0.95) | TAAR1IDO1HRH1MPOGPR52 | |
| Hydrochloric Acid SCHEMBL533785 | 0.82 | TAAR1 (0.95) | TAAR1IDO1HRH1MPOGPR52 | |
| SCHEMBL8071390 | 0.80 | TAAR1 (0.56) | TAAR1IDO1GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745313-A | The D3 dopamine-receptor stimulant for treating dyskinesia in Parkinson's disease | 德雷克塞尔大学 | 2019-05-14 | — | — | CN | claimed |
| CN-105848655-B | For attention and cognitive disorder and for dementia associated with neurodegeneration obstacle new treatment | 德雷克塞尔大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-109745313-A | The D3 dopamine-receptor stimulant for treating dyskinesia in Parkinson's disease | 德雷克塞尔大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-103347517-B | Treatment of dyskinesia in Parkinson's disease D3Dopamine receptor agonists | 德雷克塞尔大学 | 2018-10-02 | — | — | CN | disclosed |
| CN-105848655-A | Novel treatments for attention and cognitive disorders, and for dementia associated with a neurodegenerative disorder | 德雷克塞尔大学 | 2016-08-10 | — | — | CN | disclosed |