Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.88 |
| ▸ | DAO | P14920 | 1/20 | 0.88 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.88 |
| ▸ | CES2 | O00748 | 3/20 | 0.70 |
| ▸ | CES1 | P23141 | 3/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27673737 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL16486485 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL120680 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27721786 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL19104 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28394135 | 0.97 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL395154 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8671975 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10750788 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL14629919 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104150518-B | Hydrocalumite synthetic method and hydrocalumite base PVC composite heat stabilizer thereof | 邵阳天堂助剂化工有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-115746396-A | Perchlorate modified hydrotalcite and preparation method thereof, composite heat stabilizer and preparation method thereof, and leather product | 加通汽车内饰(常熟)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746402-A | Perchlorate modified hydrotalcite and preparation method thereof, composite heat stabilizer and preparation method thereof, and leather product | 加通汽车内饰(常熟)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746401-A | Perchlorate-modified hydrotalcite, preparation method thereof at normal temperature, composite heat stabilizer, preparation method thereof and leather product | 加通汽车内饰(常熟)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115467171-A | Chlorine-containing resin composition for manufacturing automobile interior leather, leather used for automobile interior and preparation method thereof | 加通汽车内饰(常熟)有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-104150518-B | Hydrocalumite synthetic method and hydrocalumite base PVC composite heat stabilizer thereof | 邵阳天堂助剂化工有限公司 | 2016-09-28 | — | — | CN | disclosed |