Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL437272 | 0.95 | LMNA (0.59) | LMNATSHRF2TDP1KMT2A | |
| Propane SCHEMBL3711418 | 0.93 | LMNA (0.57) | LMNATSHRF2TDP1KMT2A | |
| Butane SCHEMBL27396437 | 0.93 | LMNA (0.62) | LMNATSHRF2TDP1KMT2A | |
| Ethane SCHEMBL455951 | 0.91 | TSHR (0.62) | LMNATSHRF2TDP1KMT2A | |
| Hydrogen Peroxide SCHEMBL11489043 | 0.91 | LMNA (0.67) | LMNATSHRF2TDP1KMT2A | |
| Benzene SCHEMBL10686034 | 0.91 | LMNA (0.67) | LMNATSHRF2TDP1KMT2A | |
| SCHEMBL27265493 | 0.91 | LMNA (0.67) | LMNATSHRF2TDP1KMT2A | |
| Hydrogen Peroxide SCHEMBL2929887 | 0.91 | LMNA (0.67) | LMNATSHRF2TDP1KMT2A | |
| SCHEMBL1816 | 0.91 | LMNA (0.67) | LMNATSHRF2TDP1KMT2A | |
| Butanone SCHEMBL10420714 | 0.90 | LMNA (0.53) | LMNATSHRF2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105767458-A | Compound Chinese herbal medicine mixture used to increase laying hen egg production amount | 天津君合心科技发展有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-105767458-A | Compound Chinese herbal medicine mixture used to increase laying hen egg production amount | 天津君合心科技发展有限公司 | 2016-07-20 | — | — | CN | disclosed |