SCHEMBL28089718

SCHEMBL28089718

C[Hf]C.c1ccc(C(c2ccccc2)C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
CYP1A2 P05177 1/20 0.40
TSHR P16473 1/20 0.40
GPR3 P46089 2/20 0.38
CACNA1G O43497 1/20 0.35
TAAR1 Q96RJ0 2/20 0.33
HTR2A P28223 2/20 0.33
CYP19A1 P11511 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
CYP2D6 P10635 1/20 0.32
LMNA P02545 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157929 0.92 MEN1 (0.52) POLBMEN1KMT2AATMCYP1A2
SCHEMBL3157883 0.82 MEN1 (0.43) POLBMEN1KMT2AATMCYP1A2
SCHEMBL10455242 0.79 MEN1 (0.53) POLBMEN1KMT2AATMCYP1A2
SCHEMBL12814950 0.77 MEN1 (0.43) POLBMEN1KMT2AATMCYP1A2
SCHEMBL12815719 0.76 MEN1 (0.42) POLBMEN1KMT2AATMCYP1A2
SCHEMBL13241744 0.76 ESR1 (0.41) POLBMEN1KMT2AATMCYP1A2
SCHEMBL3157081 0.76 C3AR1 (0.39) POLBMEN1KMT2AATMCYP1A2
SCHEMBL2872054 0.76 NPC1 (0.41) POLBMEN1KMT2AATMCYP1A2
Hydrochloric Acid SCHEMBL8677554 0.75 MEN1 (0.44) POLBMEN1KMT2AATMCYP1A2
Hydrochloric Acid SCHEMBL12815046 0.74 MEN1 (0.41) POLBMEN1KMT2AATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104854150-B Activator compositions, their preparation, and their use in catalysts 阿尔比马尔公司 2017-05-24 CN disclosed
CN-103380154-B Activator composition, its preparation and the purposes in catalysis thereof 阿尔比马尔公司 2016-08-24 CN disclosed