SCHEMBL3157883

SCHEMBL3157883

Cc1ccc(C(c2ccc(C)cc2)C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
POLB P06746 2/20 0.43
ATM Q13315 1/20 0.43
LMNA P02545 3/20 0.42
GPR3 P46089 1/20 0.39
TSHR P16473 2/20 0.37
CYP1A2 P05177 2/20 0.37
ELANE P08246 1/20 0.36
MAPT P10636 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HKDC1 Q2TB90 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CHRNA7 P36544 1/20 0.35
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.35
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472538 0.88 MEN1 (0.42) MEN1KMT2APOLBATMLMNA
SCHEMBL3157929 0.85 MEN1 (0.52) MEN1KMT2APOLBATMGPR3
SCHEMBL3157081 0.82 C3AR1 (0.39) MEN1KMT2APOLBATMLMNA
SCHEMBL12815719 0.82 MEN1 (0.42) MEN1KMT2APOLBATMLMNA
SCHEMBL13241744 0.82 ESR1 (0.41) MEN1KMT2APOLBATMTSHR
SCHEMBL2872054 0.81 NPC1 (0.41) MEN1KMT2APOLBATMLMNA
SCHEMBL12814950 0.79 MEN1 (0.43) MEN1KMT2APOLBATMGPR3
SCHEMBL14427580 0.78 MEN1 (0.55) MEN1KMT2APOLBLMNATSHR
SCHEMBL15617718 0.76 PPIA (0.46) MEN1KMT2APOLBATMLMNA
SCHEMBL6675583 0.75 GPR3 (0.46) MEN1KMT2APOLBATMGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1988104-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985637-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
EP-1614699-B9 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2009-12-16 EP disclosed
US-7488789-B2 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-02-10 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed