Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 15/20 | 0.60 |
| ▸ | JAK2 | O60674 | 12/20 | 0.60 |
| ▸ | JAK1 | P23458 | 12/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279041 | 0.83 | SYK (0.83) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL19596097 | 0.82 | JAK3 (0.67) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL17412959 | 0.82 | SYK (0.57) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL18733444 | 0.82 | SYK (0.57) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL12148017 | 0.82 | JAK3 (0.80) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL2282223 | 0.81 | SYK (0.64) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL2277240 | 0.80 | SYK (0.69) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL2282968 | 0.80 | SYK (0.63) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL2282301 | 0.80 | SYK (0.63) | SYKCYP2C9JAK3JAK2JAK1 | |
| SCHEMBL14575030 | 0.80 | ATR (0.56) | SYKCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |