SCHEMBL28090104

SCHEMBL28090104

CC12CC3CC(C)(C1)CC(c1ccccc1)(C3)C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 9/20 0.49
GRIN2A Q12879 9/20 0.49
GRIN2D O15399 8/20 0.49
GRIN3B O60391 8/20 0.49
GRIN2B Q13224 8/20 0.49
GRIN2C Q14957 8/20 0.49
GRIN3A Q8TCU5 8/20 0.49
EPHX2 P34913 6/20 0.44
LMNA P02545 2/20 0.41
SLC22A1 O15245 1/20 0.41
ESR1 P03372 1/20 0.41
ADRB3 P13945 1/20 0.41
ACHE P22303 1/20 0.41
OPRK1 P41145 1/20 0.41
MTOR P42345 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293230 0.87 GRIN1 (0.63) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL27847918 0.85 SLC6A2 (0.43) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL6939188 0.83 GRIN2D (0.57) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL25458202 0.83 GRIN2D (0.64) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20672831 0.83 MEN1 (0.57) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20659904 0.83 ALDH1A1 (0.46) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20672519 0.83 ALDH1A1 (0.46) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20659918 0.83 ALDH1A1 (0.46) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20672518 0.83 ALDH1A1 (0.46) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL20660477 0.83 GRIN2D (0.40) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592034-B A kind of synthetic method of 1,3-diamino-phenyl-5,7-dimethyladamantane 中钢集团鞍山热能研究院有限公司 2016-07-20 CN disclosed
CN-101031606-B Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE CO 2011-03-02 CN disclosed