SCHEMBL28090125

SCHEMBL28090125

C=C(C)c1cccc([SiH2]N(CCCC)CCCC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
DRD2 P14416 2/20 0.34
OPRM1 P35372 2/20 0.34
DRD3 P35462 2/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
PTGS2 P35354 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28090013 0.84 SMN1; SMN2 (0.33) HPGDALDH1A1SMN1; SMN2
SCHEMBL28090112 0.81 GAA (0.35) HPGDDRD3GAALMNAHDAC1
SCHEMBL29514981 0.79 ALDH1A1 (0.34) HPGDALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL608130 0.79 ALDH1A1 (0.34) HPGDALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL611339 0.79 ALDH1A1 (0.34) HPGDALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL608131 0.77 SMN1; SMN2 (0.35) HPGDALDH1A1SMN1; SMN2GAA
SCHEMBL28090042 0.76 MEN1 (0.35) ALDH1A1LMNA
SCHEMBL609798 0.75 GBA1 (0.31)
SCHEMBL29515112 0.75 GBA1 (0.31)
SCHEMBL28196616 0.75 TDP1 (0.40) ALDH1A1DRD2OPRM1DRD3OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed