Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599496 | 0.86 | HSD17B1 (0.52) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL29429121 | 0.84 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL26979937 | 0.84 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL29696046 | 0.84 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL272034 | 0.84 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| Hydrogen Sulfide SCHEMBL6269773 | 0.82 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL3811825 | 0.82 | HSD17B1 (0.72) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| Hydrogen Sulfide SCHEMBL22042810 | 0.82 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL13589555 | 0.82 | HSD17B1 (0.72) | HSD17B1HSD17B2ESR2TP53TDP1 | |
| SCHEMBL21790498 | 0.81 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| US-7556902-B2 | Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof | RICOH COMPANY, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20060046169-A1 | Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof | RICOH COMPANY, LTD. (JP) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | HSD17B1 603/4885HSD17B2 923/4885ESR2 2064/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | HSD17B1 360/4885HSD17B2 740/4885ESR2 3700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.