Carbamic Acid

Carbamic Acid

SCHEMBL28090504

CC(=O)OC(C)(C)C.NC(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
ACHE P22303 1/20 0.39
DGAT1 O75907 1/20 0.37
LMNA P02545 1/20 0.37
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
ALDH1A1 P00352 4/20 0.33
TSHR P16473 3/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC7A5 Q01650 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL28017647 0.92 LMNA (0.47) GAADGAT1LMNAALOX15BLM
Hydrogen Peroxide SCHEMBL3021120 0.91 GAA (0.48) GAADGAT1LMNAALDH1A1TSHR
Acetic Acid SCHEMBL2928244 0.88 GAA (0.46) GAADGAT1ALDH1A1TSHRFFAR3
Bicarbonate SCHEMBL28020933 0.88 GAA (0.46) GAADGAT1ALDH1A1TSHRFFAR3
Acetic Acid SCHEMBL28991773 0.88 GAA (0.46) GAADGAT1ALDH1A1TSHRFFAR3
Acetic Acid SCHEMBL25259384 0.88 GAA (0.46) GAADGAT1ALDH1A1TSHRFFAR3
Methylamine SCHEMBL28787480 0.88 GAA (0.46) GAADGAT1LMNAALOX15BLM
SCHEMBL28358909 0.88 GAA (0.50) GAADGAT1LMNAALDH1A1TSHR
SCHEMBL26684 0.88
SCHEMBL28745990 0.88 GAA (0.50) GAADGAT1LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768792-A Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2023-09-19 CN disclosed
CN-105745214-B Tricyclic piperidine compounds 埃科特莱茵药品有限公司 2019-02-19 CN disclosed
CN-108117546-A ATP-binding cassette transport protein conditioning agent 弗特克斯药品有限公司 2018-06-05 CN disclosed
CN-105143222-B Glycosidase inhibitor 默克专利有限公司 2018-02-02 CN disclosed
CN-103534258-B Tyrosine kinase inhibitor 普林斯匹亚生物制药公司 2016-09-14 CN disclosed
CN-103339138-B Selective glycosidase inhibitors and application thereof 阿勒克图治疗公司 2016-08-31 CN disclosed