SCHEMBL28090547

SCHEMBL28090547

B.c1ccc2cscc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.47
ALOX12 P18054 1/20 0.47
ALDH1A1 P00352 6/20 0.44
HSD17B10 Q99714 5/20 0.44
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
HPRT1 P00492 1/20 0.40
MAPT P10636 3/20 0.39
CYP1B1 Q16678 2/20 0.36
NQO2 P16083 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP2B6 P20813 2/20 0.35
CYP2E1 P05181 1/20 0.33
PAX8 Q06710 1/20 0.32
TRPM4 Q8TD43 1/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240787 0.96
SCHEMBL51694 0.96
Bromide SCHEMBL29262820 0.90 CYP2A6 (0.44) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
Formaldehyde SCHEMBL28853578 0.87 CYP2A6 (0.41) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
SCHEMBL1172873 0.84 CYP2A6 (0.39) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
SCHEMBL29262819 0.84 CYP2A6 (0.39) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
Boric Acid SCHEMBL30102650 0.84 CYP2A6 (0.39) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
SCHEMBL440327 0.80 ALDH1A1 (0.42) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
SCHEMBL8904326 0.78 ALDH1A1 (0.46) CYP2A6ALOX12ALDH1A1HSD17B10TSHR
SCHEMBL8905235 0.78 ALDH1A1 (0.46) CYP2A6ALOX12ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105949246-B A kind of double-nuclear ring metal complex of iridium and its preparation method and application 苏州纳凯科技有限公司 2019-04-23 CN disclosed
CN-105949246-A Dinuclear cyclic metal iridium complex as well as preparation method and application thereof 苏州纳凯科技有限公司 2016-09-21 CN disclosed