Guaiacol

Guaiacol

SCHEMBL28090557

C=CC(=O)O.CCCC.COc1ccccc1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
TP53 P04637 2/20 0.58
TSHR P16473 2/20 0.58
MAPT P10636 4/20 0.44
KDM4E B2RXH2 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
MAPK1 P28482 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
POLB P06746 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 4/20 0.43
LMNA P02545 3/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiacol SCHEMBL11150002 0.93 CA1 (0.67) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL811953 0.84 TP53 (0.82) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL10489296 0.84 TSHR (0.50) CA1CA2TP53TSHRMAPT
1-Hydroxy-2-Propoxybenzene SCHEMBL28408739 0.83 GAA (0.53) MAPTKDM4ENPC1RAB9ASMN1; SMN2
1,2-Dimethoxybenzene SCHEMBL29004764 0.82 CA1 (0.56) CA1CA2TP53TSHRMAPT
1-Hydroxy-2-Ethoxybenzene SCHEMBL11580144 0.82 GLA (0.53) MAPTKDM4ETDP1MAPK1RAB9A
Guaiacol SCHEMBL29249272 0.81 TP53 (0.69) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL27884623 0.81 CA1 (0.69) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL4089861 0.81 CA1 (0.69) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL21542 0.80 CA1 (0.82) CA1CA2TP53TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105778822-A Special pressure-sensitive adhesive for traditional Chinese medicine sticky plasters 党庆风 2016-07-20 CN disclosed