Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6235903 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL8421151 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL5140509 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL29098772 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28072623 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL25396149 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL15662076 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL15662074 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL7924520 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL188477 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216654506-U | Supergravity liquid-gas mixing acceleration reactor | 南京亨格水处理科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-104220413-B | Method for producing 4-hydroxybutyl acrylate | 大阪有机化学工业株式会社 | 2018-12-04 | — | — | CN | disclosed |
| CN-105339341-B | Production system for (meth) acrylic acid ester | 大阪有机化学工业株式会社 | 2018-02-13 | — | — | CN | disclosed |
| CN-103965838-B | A kind of high-temperature phase-change heat storage material and preparation method thereof | 武汉理工大学 | 2016-08-17 | — | — | CN | disclosed |