Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.96 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671016 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3665297 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL21104687 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL28720089 | 0.98 | GAA (0.93) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3668041 | 0.98 | GAA (1.00) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL664938 | 0.90 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL27818229 | 0.90 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL7751819 | 0.83 | GAA (0.73) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3665477 | 0.81 | GAA (0.71) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL4153139 | 0.81 | GAA (0.71) | GAAL3MBTL1EPHX1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873927-B | 4-azaindole derivatives | 卫材R&D管理有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105873927-A | 4-azaindole derivatives | 卫材R&D管理有限公司 | 2016-08-17 | — | — | CN | disclosed |