SCHEMBL28091564

SCHEMBL28091564

CCCCCOc1ccccc1C(=O)c1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
LMNA P02545 5/20 0.58
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
NR1I2 O75469 1/20 0.58
CHRM2 P08172 1/20 0.58
CYP3A4 P08684 1/20 0.58
ADRA2A P08913 1/20 0.58
OPRK1 P41145 1/20 0.58
HTR2B P41595 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
NPC1 O15118 1/20 0.51
STS P08842 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CNR2 P34972 2/20 0.49
HPGD P15428 1/20 0.49
ATM Q13315 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29813631 0.99 LMNA (0.60) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL7252531 0.87 LMNA (0.66) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL30603177 0.86 KMT2A (0.56) MAPTLMNAKMT2ACYP3A4SMN1; SMN2
SCHEMBL2469614 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL536375 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL17203917 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL28499831 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL5898795 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL6433586 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL11216088 0.86 LMNA (0.68) MAPTLMNAKMT2AMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104144996-B The binding agent that microstructured optical is transparent 3M创新有限公司 2016-10-12 CN disclosed