Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16741926 | 0.86 | RAD52 (0.54) | PPARGPOLBRAD52ALDH1A1HPGD | |
| SCHEMBL18263084 | 0.86 | PPARG (0.49) | PPARGALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL18262994 | 0.85 | PPARG (0.48) | PPARGPOLBRAD52ALDH1A1MEN1 | |
| SCHEMBL18966441 | 0.85 | HPGD (0.66) | PPARGPOLBRAD52ALDH1A1HPGD | |
| SCHEMBL18263009 | 0.84 | PPARG (0.47) | PPARGPOLBRAD52ALDH1A1MEN1 | |
| SCHEMBL18941207 | 0.84 | RAD52 (0.61) | PPARGPOLBRAD52ALDH1A1HPGD | |
| SCHEMBL27542798 | 0.83 | RAB9A (0.54) | PPARGPOLBRAD52ALDH1A1HPGD | |
| SCHEMBL335702 | 0.81 | RAB9A (0.63) | PPARGALDH1A1HPGDRAB9AMEN1 | |
| SCHEMBL18941094 | 0.81 | RAD52 (0.58) | PPARGPOLBRAD52CNR2RAB9A | |
| SCHEMBL27734727 | 0.80 | PPARG (0.74) | PPARGRAD52ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916841-A | Functionalised and substituted indoles as anti-cancer agents | 诺沃根公司 | 2016-08-31 | — | — | CN | disclosed |