Anthraquinone

Anthraquinone

SCHEMBL28092013

CN1CC(O)c2ccccc21.O=C1c2ccccc2C(=O)c2ccccc21

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
EGFR P00533 2/20 0.41
MAPK1 P28482 2/20 0.41
LMNA P02545 1/20 0.41
ATM Q13315 1/20 0.41
BRD4 O60885 1/20 0.40
CCKBR P32239 1/20 0.40
CES1 P23141 2/20 0.40
TTR P02766 1/20 0.40
CDC25B P30305 1/20 0.39
BCHE P06276 1/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
GPR3 P46089 1/20 0.38
ALDH1A1 P00352 2/20 0.37
NOTUM Q6P988 1/20 0.37
RAF1 P04049 1/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30509271 0.88 NOTUM (0.41) KMT2AMAPTMEN1LMNAMTNR1A
SCHEMBL27903243 0.88 NOTUM (0.41) KMT2AMAPTMEN1LMNAMTNR1A
SCHEMBL20723806 0.71 NOTUM (0.38) KMT2AMEN1ATMALDH1A1NOTUM
SCHEMBL2614632 0.70 KDM4C (0.40) GPR3NOTUM
SCHEMBL19047042 0.70 SLC6A2 (0.39) KMT2AMEN1LMNAMTNR1AMTNR1B
SCHEMBL16079966 0.70 SLC6A2 (0.39) KMT2AMEN1LMNAMTNR1AMTNR1B
SCHEMBL12923931 0.70 KDM4C (0.40) GPR3NOTUM
SCHEMBL12923936 0.70 KDM4C (0.40) GPR3NOTUM
SCHEMBL19047039 0.70 SLC6A2 (0.39) KMT2AMEN1LMNAMTNR1AMTNR1B
SCHEMBL15216876 0.69 ALDH1A1 (0.41) KMT2AMAPTEGFRMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103517985-B Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 诺维信公司 2016-12-07 CN disclosed