Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 15/20 | 0.41 |
| ▸ | CES1 | P23141 | 11/20 | 0.41 |
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494438 | 0.78 | ADH1C (0.38) | MEN1KMT2AHSD17B10 | |
| SCHEMBL7689401 | 0.76 | ADH1C (0.37) | EPHX1FAAHMEN1CYP1A2KMT2A | |
| SCHEMBL6575288 | 0.74 | EPHX1 (0.49) | EPHX1FAAHCES1CES2MEN1 | |
| SCHEMBL28166981 | 0.73 | ADH1C (0.45) | EPHX1FAAH | |
| SCHEMBL27870138 | 0.73 | ADH1C (0.45) | EPHX1FAAH | |
| SCHEMBL8523736 | 0.71 | ADH1C (0.41) | EPHX1FAAH | |
| SCHEMBL7439163 | 0.71 | ADH1C (0.46) | EPHX1FAAH | |
| SCHEMBL19949895 | 0.70 | EPHX1 (0.47) | EPHX1FAAHCES1CES2MEN1 | |
| SCHEMBL7541904 | 0.69 | EPHX1 (0.80) | EPHX1FAAHCES1CES2MEN1 | |
| SCHEMBL7545639 | 0.69 | EPHX1 (0.80) | EPHX1FAAHCES1CES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873930-B | Novel bicyclic compounds and their use as antibacterial agents and β -lactamase inhibitors | 费多拉制药公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-105873930-A | Novel bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors | 费多拉制药公司 | 2016-08-17 | — | — | CN | disclosed |