SCHEMBL28092549

SCHEMBL28092549

CC(C)(C)Cc1ccc(O)cc1.[MgH2]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.95
ESR2 Q92731 8/20 0.61
BLM P54132 1/20 0.53
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
SHBG P04278 1/20 0.46
ABAT P80404 1/20 0.44
LMNA P02545 1/20 0.44
TYR P14679 1/20 0.44
CYP3A4 P08684 1/20 0.44
AR P10275 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73405 0.97 ESR1 (1.00) ESR1ESR2BLMTHRATHRB
SCHEMBL23734534 0.91 ESR1 (0.86) ESR1ESR2BLMTHRATHRB
SCHEMBL6685103 0.84 ESR1 (0.74) ESR1ESR2BLMTHRATHRB
SCHEMBL20642196 0.80 ESR1 (0.68) ESR1ESR2BLMTHRATHRB
SCHEMBL1068241 0.80 ESR1 (0.70) ESR1ESR2BLMABATLMNA
SCHEMBL16383543 0.79 ESR1 (0.68) ESR1ESR2BLMSHBGABAT
SCHEMBL23734261 0.79 ESR1 (0.66) ESR1ESR2BLMTHRATHRB
SCHEMBL564410 0.78 ESR1 (0.67) ESR1ESR2BLMABATSLC6A2
SCHEMBL8191949 0.78 ESR1 (0.67) ESR1ESR2BLMABATLMNA
SCHEMBL358742 0.77 ESR1 (0.65) ESR1ESR2BLMTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050214-A Method for producing fluorinated solid oxides and use thereof in metallocene-based catalyst systems 切弗朗菲利浦化学公司 2023-11-14 CN disclosed
CN-112672821-B Method for producing fluorinated solid oxides and use thereof in metallocene-based catalyst systems 切弗朗菲利浦化学公司 2023-11-07 CN disclosed
CN-110678534-B Lubricant composition containing hexene-based oligomers 切弗朗菲利浦化学公司 2022-02-11 CN disclosed
CN-107922540-B Ziegler-NATTA (ZIEGLER-NATTA) -metallocene dual catalyst system with activator-support 切弗朗菲利浦化学公司 2021-05-14 CN disclosed
CN-112672821-A Method for producing fluorinated solid oxides and use thereof in metallocene-based catalyst systems 切弗朗菲利浦化学公司 2021-04-16 CN disclosed
CN-108026220-B Heterogeneous ziegler-natta catalyst with fluorinated silica-coated alumina 切弗朗菲利浦化学公司 2020-10-27 CN disclosed
CN-110678534-A Lubricant composition containing hexene-based oligomers 切弗朗菲利浦化学公司 2020-01-10 CN disclosed
CN-110536910-A Contain Low-valent Titanium-aluminium complex antigravity system and the polymer produced by it CHEVRON PHILLIPS CHEMICAL CO LP 2019-12-03 CN disclosed
CN-104371050-B The metallocene of sub- cyclobutyl bridging and antigravity system comprising it 切弗朗菲利浦化学公司 2019-02-19 CN disclosed
CN-104418963-B Higher density polyolefin with improved stress cracking resistance 切弗朗菲利浦化学公司 2018-07-10 CN disclosed
CN-104292368-B The method for generating the aluminum oxide activating agent carrier of fluorination-chlorided silica-cladding and the catalyst system containing it 切弗朗菲利浦化学公司 2018-05-22 CN disclosed
CN-108026220-A Heterogeneous Ziegler-Natta catalyst with fluorinated silica-coated alumina 切弗朗菲利浦化学公司 2018-05-11 CN disclosed
CN-107922539-A The heterogeneous Ziegler Natta catalyst of the aluminium oxide through coated with silica with fluorination 切弗朗菲利浦化学公司 2018-04-17 CN disclosed
CN-107922540-A Ziegler-Natta (ZIEG L ER-NATTA) -metallocene dual catalyst system with activator-support 切弗朗菲利浦化学公司 2018-04-17 CN disclosed
CN-104004116-B Dual activator carried catalyst system 切弗朗菲利浦化学公司 2018-03-09 CN disclosed
CN-103183700-B Catalyst compositions for the polymerization of olefins 切弗朗菲利浦化学公司 2017-05-17 CN disclosed
CN-105849138-A Catalyst systems containing boron-bridged cyclopentadienyl-fluorenyl metallocene compounds having alkenyl substituents 切弗朗菲利浦化学公司 2016-08-10 CN disclosed