Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734534 | 0.87 | ESR1 (0.86) | ESR1ESR2BLMTHRATHRB | |
| SCHEMBL20642196 | 0.84 | ESR1 (0.68) | ESR1ESR2BLMTHRATHRB | |
| SCHEMBL73405 | 0.81 | ESR1 (1.00) | ESR1ESR2BLMTHRATHRB | |
| SCHEMBL24940008 | 0.80 | MMP1 (0.43) | ESR1SLC6A2SLC6A3KDM4ELMNA | |
| SCHEMBL28092549 | 0.79 | ESR1 (0.95) | ESR1ESR2BLMTHRATHRB | |
| SCHEMBL24517925 | 0.74 | ESR1 (0.42) | ESR1THRATHRBSLC6A2SLC6A4 | |
| SCHEMBL16383543 | 0.74 | ESR1 (0.68) | ESR1ESR2BLMSHBGSLC6A2 | |
| SCHEMBL19341333 | 0.74 | CYP2A6 (0.59) | ESR1ALDH1A1CYP3A4HTR2CHSD17B10 | |
| SCHEMBL22063921 | 0.72 | ESR1 (0.58) | ESR1ESR2SHBGSLC6A2SLC6A4 | |
| SCHEMBL19259341 | 0.72 | ESR1 (0.65) | ESR1ESR2BLMSHBGADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084847-B2 | Polyamide compound and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084847-B2 | Polyamide compound and use thereof | OPRK1, OPRM1, OPRD1 | ESR1 1766/4885ESR2 1494/4885BLM 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.