Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28092587

N.Nc1cc(Br)c(N)cc1Br

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 2/20 0.48
APAF1 O14727 1/20 0.48
THRB P10828 1/20 0.48
NR4A1 P22736 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PTPN11 Q06124 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GAA P10253 2/20 0.42
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
PTK2 Q05397 1/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519306 0.96 MAPT (0.50) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL17549722 0.89 PTK2 (0.57) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL4442830 0.89 POLB (0.48) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL5525224 0.85 PTK2 (0.50) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL1503418 0.83 POLB (0.42) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL3439643 0.81 CYP3A4 (0.63) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL2244271 0.80 PTK2 (0.54) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL29400454 0.80 PTK2 (0.54) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL21597029 0.78 KDM1A (0.43) KMT2AALDH1A1POLBL3MBTL1MAPT
SCHEMBL9068413 0.78 CYP3A4 (0.46) KMT2AALDH1A1POLBL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814066-A Azaborinine derivatives, their synthesis and use in organic electronic devices 默克专利股份有限公司 2016-07-27 CN disclosed