Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000521 | 0.92 | TSHR (0.67) | TSHRLMNAKMT2AMEN1CA12 | |
| SCHEMBL27522 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL27575104 | 0.90 | — | — | |
| Propane SCHEMBL8063536 | 0.87 | TSHR (0.60) | TSHRLMNAKMT2AMEN1CA12 | |
| Acetic Acid SCHEMBL28820394 | 0.85 | TSHR (0.57) | TSHRLMNAKMT2AMEN1CA12 | |
| Tetrahydrothiophene SCHEMBL11870552 | 0.85 | TSHR (0.46) | TSHRLMNAEPHX2KMT2AMEN1 | |
| SCHEMBL11870556 | 0.83 | TSHR (0.44) | TSHRLMNAEPHX2KMT2AMEN1 | |
| SCHEMBL15902482 | 0.79 | GAA (0.52) | TSHRKMT2AMEN1ALDH1A1MGAM | |
| SCHEMBL1357249 | 0.79 | TSHR (0.50) | TSHRLMNAKMT2AMEN1CA12 | |
| Cyclohexane SCHEMBL1289332 | 0.79 | TSHR (0.74) | TSHRLMNAEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-105980387-A | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2016-09-28 | — | — | CN | disclosed |