SCHEMBL28094036

SCHEMBL28094036

Cc1ccc(CCNC2CCCNC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.43
KDM4E B2RXH2 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CDK2AP1 O14519 1/20 0.40
CHEK1 O14757 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
GRIN2B Q13224 1/20 0.38
KCNH2 Q12809 1/20 0.38
CCNK O75909 1/20 0.37
CDK7 P50613 1/20 0.37
CCNH P51946 1/20 0.37
MNAT1 P51948 1/20 0.37
CDK12 Q9NYV4 1/20 0.37
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28038612 0.99 KDM1A (0.42) KDM1AKDM4ETAAR1CDK2AP1CHEK1
Hydrochloric Acid SCHEMBL28698584 0.99 KDM1A (0.42) KDM1AKDM4ETAAR1CDK2AP1CHEK1
SCHEMBL22255203 0.88 KDM4E (0.44) KDM4ETAAR1HRH3GRIN2B
SCHEMBL10496394 0.85 TAAR1 (0.57) KDM1ATAAR1GRIN2B
SCHEMBL14813680 0.85 TAAR1 (0.57) KDM1ATAAR1GRIN2B
SCHEMBL4207773 0.81 SOS1 (0.46) KDM4ETAAR1HRH3GRIN2B
SCHEMBL18677179 0.81 TAAR1 (0.59) KDM4ETAAR1HRH3GRIN2B
SCHEMBL2466540 0.79 GRIN2B (0.51) KDM4ETAAR1HRH3GRIN2B
SCHEMBL28215970 0.75 GRIN2B (0.57) KDM1ATAAR1GRIN2BKCNH2
SCHEMBL20273868 0.75 KCNH2 (0.50) KDM1AHRH3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835631-B Preparation method of cis-1-benzyl-4-methyl-3-methylamino-piperidine dihydrochloride 重庆恩联生物科技有限公司 2024-02-13 CN disclosed
CN-105906553-A Synthesis method of N-benzyl-4-methylpiperidine-3-one hydrochloride 重庆威尔德·浩瑞医药化工有限公司 2016-08-31 CN disclosed