Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30638147 | 1.00 | GRIN2B (0.57) | GRIN2BTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14813680 | 0.90 | TAAR1 (0.57) | GRIN2BTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10496394 | 0.90 | TAAR1 (0.57) | GRIN2BTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7317273 | 0.90 | GRIN2B (0.65) | GRIN2BTAAR1SOS1OPRM1OPRL1 | |
| SCHEMBL20445923 | 0.84 | KCNH2 (0.43) | GRIN2BTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL605459 | 0.83 | SLC6A2 (0.63) | GRIN2BSLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL239923 | 0.83 | SLC6A2 (0.63) | GRIN2BSLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL4766363 | 0.83 | SLC6A2 (0.63) | GRIN2BSLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL18994881 | 0.82 | MAOA (0.42) | GRIN2BTAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL697480 | 0.81 | SLC6A2 (0.61) | GRIN2BSLC6A2SLC6A4SLC6A3SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | claimed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | claimed |
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-109153671-A | There is the active oxinane of multi-mode and thiapyran derivative for pain | 埃斯蒂文制药股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108137608-A | Janus kinase 1 selective inhibitor and pharmaceutical application thereof | 阳智化学（株） | 2018-06-08 | — | — | CN | disclosed |
| CN-107922384-A | Amide derivatives having multimodal activity on pain | 埃斯蒂文博士实验室股份有限公司 | 2018-04-17 | — | — | CN | disclosed |